检索范围:
排序: 展示方式:
Analysis on carbon emission reduction intensity of fuel cell vehicles from a life-cycle perspective
《能源前沿(英文)》 doi: 10.1007/s11708-023-0909-1
关键词: hydrogen energy life-cycle assessment (LCA) fuel cell vehicle carbon emission energy cost
Discovery of small molecule degraders for modulating cell cycle
《医学前沿(英文)》 页码 823-854 doi: 10.1007/s11684-023-1027-5
The role of CDK1 siRNA interference in cell cycle and cell apoptosis
Hui XIAO PhD, Ming TIAN MM, Junna GE MM, Xin Wei MD, Zhaoming LI MM, Xiaolan LI MS, Deding TAO PhD, Junbo HU MD, Jianping GONG MD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 384-389 doi: 10.1007/s11684-009-0070-1
关键词: cyclin-dependent kinase1 siRNA interference cell cycle apoptosis
SU Yuan, JIN Yang, ZHANG Xiaoju, ZHOU Qiong, BAI Ming, ZHU Liping
《医学前沿(英文)》 2007年 第1卷 第4期 页码 359-363 doi: 10.1007/s11684-007-0069-4
Effects of galectin-3 inhibition on endometrial cell cycle and adhesion
LEI Caixia, ZHANG Wei, SUN Xiaowei, DU Guoping, WANG Li, LIU Yinkun
《医学前沿(英文)》 2007年 第1卷 第4期 页码 390-397 doi: 10.1007/s11684-007-0076-5
DU Xiang, ZHAO Hongguang, GUO Wei, GONG Shouliang, WANG Wen
《医学前沿(英文)》 2008年 第2卷 第2期 页码 204-206 doi: 10.1007/s11684-008-0039-5
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 108-112 doi: 10.1007/s11684-009-0015-8
关键词: celecoxib CD437 melanoma A375 cell apoptosis cycle arrest
Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN
《农业科学与工程前沿(英文)》 2014年 第1卷 第3期 页码 250-257 doi: 10.15302/J-FASE-2014031
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
《能源前沿(英文)》 2018年 第12卷 第3期 页码 466-480 doi: 10.1007/s11708-018-0561-3
Fuel cell vehicles, as the most promising clean vehicle technology for the future, represent the major chances for the developing world to avoid high-carbon lock-in in the transportation sector. In this paper, by taking China as an example, the unique advantages for China to deploy fuel cell vehicles are reviewed. Subsequently, this paper analyzes the greenhouse gas (GHG) emissions from 19 fuel cell vehicle utilization pathways by using the life cycle assessment approach. The results show that with the current grid mix in China, hydrogen from water electrolysis has the highest GHG emissions, at 3.10 kgCO2/km, while by-product hydrogen from the chlor-alkali industry has the lowest level, at 0.08 kgCO2/km. Regarding hydrogen storage and transportation, a combination of gas-hydrogen road transportation and single compression in the refueling station has the lowest GHG emissions. Regarding vehicle operation, GHG emissions from indirect methanol fuel cell are proved to be lower than those from direct hydrogen fuel cells. It is recommended that although fuel cell vehicles are promising for the developing world in reducing GHG emissions, the vehicle technology and hydrogen production issues should be well addressed to ensure the life-cycle low-carbon performance.
关键词: hydrogen fuel cell vehicle life cycle assessment energy consumption greenhouse gas (GHG) emissions China
Functional role of ATM in the cellular response to DNA damage
Ming LIU, Wenxiang HU
《化学科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 179-187 doi: 10.1007/s11705-009-0268-4
关键词: ataxia-telangiectasia mutated (ATM) cell cycle checkpoint DNA damage signalling transduction
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 379-383 doi: 10.1007/s11684-009-0073-y
关键词: p38 regulated/activated protein kinase gene knockout cell cycle cell proliferation
A comparison of production system life cycle models
Rajesh ATTRI, Sandeep GROVER
《机械工程前沿(英文)》 2012年 第7卷 第3期 页码 305-311 doi: 10.1007/s11465-012-0332-5
Companies today need to keep up with the rapidly changing market conditions to stay competitive. The main issues in this paper are related to a company’s market and its competitors. The prediction of market behavior is helpful for a manufacturing enterprise to build efficient production systems. However, these predictions are usually not reliable. A production system is required to adapt to changing markets, but such requirement entails higher cost. Hence, analyzing different life cycle models of the production system is necessary. In this paper, different life cycle models of the production system are compared to evaluate the distinctive features and the limitations of each model. Furthermore, the difference between product life cycle and production life cycle is summarized, and the effect of product life cycle on production life cycle is explained. Finally, a production system life cycle model, along with key activities to be performed in each stage, is proposed specifically for the manufacturing sector.
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 420-429 doi: 10.1007/s11684-016-0478-3
Inappropriate cell proliferation during oncogenesis is often accompanied by inactivation of components involved in the cell cycle machinery. Here, we report that cyclin-dependent kinase inhibitor 2C (CDKN2C) as a member of the cyclin-dependent kinase inhibitors is a target of the PML/RARα oncofusion protein in leukemogenesis of acute promyelocytic leukemia (APL). We found that CDKN2C was markedly downregulated in APL blasts compared with normal promyelocytes. Chromatin immunoprecipitation combined with quantitative polymerase chain reaction demonstrated that PML/RARα directly bound to the CDKN2C promoter in the APL patient-derived cell line NB4. Luciferase assays indicated that PML/RARα inhibited the CDKN2C promoter activity in a dose-dependent manner. Furthermore, all-trans retinoic acid treatment induced CDKN2C expression by releasing the PML/RARα binding on chromatin in NB4 cells. Functional studies showed that ectopic expression of CDKN2C induced a cell cycle arrest at the G0/G1 phase and a partial differentiation in NB4 cells. Finally, the transcriptional regulation of CDKN2C was validated in primary APL patient samples. Collectively, this study highlights the importance of CDKN2C inactivation in the abnormal cell cycle progression and differentiation block of APL cells and may provide new insights into the study of pathogenesis and targeted therapy of APL.
关键词: CDKN2C acute promyelocytic leukemia cell cycle arrest differentiation
基于元胞自动机的电阻存储器多比特固定型故障诊断 Research Article
Sutapa SARKAR1, Biplab Kumar SIKDAR2, Mousumi SAHA3
《信息与电子工程前沿(英文)》 2022年 第23卷 第7期 页码 1110-1126 doi: 10.1631/FITEE.2100255
关键词: 电阻存储器;电池可靠性;块级故障诊断;单长循环单吸引子元胞自动机;单长循环双吸引子元胞自动机;单长循环多吸引子元胞自动机
Improvement of the cascading closed loop cycle system
ZHANG Guoqiang, CAI Ruixian
《能源前沿(英文)》 2007年 第1卷 第3期 页码 341-346 doi: 10.1007/s11708-007-0051-5
标题 作者 时间 类型 操作
Analysis on carbon emission reduction intensity of fuel cell vehicles from a life-cycle perspective
期刊论文
The role of CDK1 siRNA interference in cell cycle and cell apoptosis
Hui XIAO PhD, Ming TIAN MM, Junna GE MM, Xin Wei MD, Zhaoming LI MM, Xiaolan LI MS, Deding TAO PhD, Junbo HU MD, Jianping GONG MD,
期刊论文
Impact of siRNA targeting pirh2 on proliferation and cell cycle control of the lung adenocarcinoma cell
SU Yuan, JIN Yang, ZHANG Xiaoju, ZHOU Qiong, BAI Ming, ZHU Liping
期刊论文
Effects of galectin-3 inhibition on endometrial cell cycle and adhesion
LEI Caixia, ZHANG Wei, SUN Xiaowei, DU Guoping, WANG Li, LIU Yinkun
期刊论文
Effects of 3-aminobenzamide on poly (ADP-ribose) polymerase expression, apoptosis and cell cycle progression
DU Xiang, ZHAO Hongguang, GUO Wei, GONG Shouliang, WANG Wen
期刊论文
Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell
Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN
期刊论文
Dynamics of foot-and-mouth disease virus replication in cells at different phases of the cell-divisioncycle
Claudia DOEL,Zhidong ZHANG,Lise MAZELET,Ryan WATERS,John BASHIRUDDIN
期刊论文
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
期刊论文
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
期刊论文
Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia
null
期刊论文